Next-Level Periodontal Regeneration

REGENFAST® in the treatment of infrabony defects

Prof. Francesco Cairo · Italy
 · July 10, 2023

BioBrief - Periodontal Treatment

The Situation

The present patient (65 years old, male, no smoker) showed stage IV, grade C, generalized periodontitis. After causal related therapy, residual pockets were scheduled for periodontal surgery. At that time, periodontal regeneration with REGENFAST® and Geistlich Bio-Oss® at central incisor was scheduled. Periodontal regeneration is the treatment of choice for residual infrabony defect according to international guidelines.


The Approach

Periodontal flap surgery including simplified papillary preservation was performed. After gentle debridement of infrabony defects, REGENFAST® was applied over exposed root and in combination with Geistlich Bio-Oss® small granules. Care was then taken to obtain primary soft tissue closure to improve healing with probing depth reduction.


The Outcome

To treat the residual pocket associated with a deep, not containing infrabony defect, REGENFAST® mixed with Geistlich Bio-Oss® small granules in combination with papillary preservation flap. One year after surgery the clinical and radiological result shows an optimal treatment outcome of the defect.
A Retrospective Case Series was published in Feb 2024.1


Keys to Success

  • Successful causal related therapy
  • Proper flap management for periodontal regeneration
  • Efficacy of REGENFAST® and Geistlich Bio-Oss® small granules
  • Excellent patient compliance

About the author

Prof. Francesco Cairo | Italy

Francesco Cairo, DDS – Periodontology and Implant Dentistry
Head of the Research Unit in Periodontology and Periodontal Medicine and Director of the full-time Master Program in Periodontology at the University of Florence, Florence, Italy. He is an active member and treasurer of the Italian Society of Periodontology (SIdP). He graduated at Siena University in 1998, then moved at Florence University where was trained in Periodontology, Implant Dentistry and Oral Surgery.