After the regenerative surgical procedure—consisting of flap elevation, debridement of the root surface, removal of the granulation tissue, filling the defect with Geistlich Bio-Oss® particles, and covering with Geistlich Bio-Gide®—three patients were randomly allocated to three treatment modalities:
- Patient without orthodontic tooth movement, serving as a control.
- Patient with orthodontic tooth movement: one tooth tilted toward the periodontal defect applying uprighting movement in combination with tension forces correlated to the defect.
- Patient with orthodontic tooth movement: one tooth was moved toward the periodontal defect applying pressure forces.
The re-entry procedure was performed at the 9-month endpoint visit, and bony core samples were harvested from the former defect sites with a microtrephine.
The authors conclude
“Following orthodontic tooth movement, increased active resorption of Geistlich Bio-Oss® along with new bone formation was observed, which needs further investigation due to the low sample size of the present study. Nevertheless, Geistlich Bio-Oss® resorption is a unique phenomenon and may be beneficial for patients treated with a combined periodontal orthodontic as it results in the long-term stability of the grafted sites.”